Table 2 In silico analysis of anti-inflammatory, anti-cancer and toxicity prediction of identified potential biologically active peptides from CWPHs P4.3 and 5.2 as revealed by their peptide ranker score, ToxinPred, Anticp and AIPpred.
From: Camel whey protein hydrolysates induced G2/M cellcycle arrest in human colorectal carcinoma
Peptide sequence | Peptide ranker score | Mol wt (g/mol) | Charge | Isoelectric point | Toxicity | AIP prediction | Anticp prediction |
|---|---|---|---|---|---|---|---|
P-4.3 | |||||||
AHLEQVLLR | 0.83 | 1078.27 | 0.1 | 7.88 | Non-toxin | AIP | Anticp |
ALPNIDPPTVER | 0.82 | 1321.48 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
AVLPFQEPVPDPVR | 0.75 | 1563.79 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
AVVSPIQF | 0.75 | 860.01 | 0 | 3.77 | Non-toxin | AIP | Anticp |
AVVSPIQFR | 0.75 | 1016.19 | 1 | 10.9 | Non-toxin | AIP | Anticp |
DDVVIK | 0.74 | 687.78 | − 1 | 3.71 | Non-toxin | AIP | Anticp |
DFLK | 0.74 | 521.61 | 0 | 6.66 | Non-toxin | AIP | Anticp |
DILK | 0.74 | 487.59 | 0 | 6.66 | Non-toxin | AIP | Anticp |
DILKEDMPSQR | 0.69 | 1331.5 | − 1 | 4.17 | Non-toxin | AIP | Anticp |
DLENLHLPLPLL | 0.68 | 1386.63 | − 1.9 | 3.92 | Non-toxin | AIP | Anticp |
DLENLHLPLPLLQ | 0.68 | 1514.76 | − 1.9 | 3.92 | Non-toxin | AIP | Anticp |
DNENLQSR | 0.66 | 974.97 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
DSALGLLR | 0.65 | 843.97 | 0 | 6.68 | Non-toxin | AIP | Anticp |
DV | 0.65 | 232.23 | − 1 | 0.72 | Non-toxin | AIP | Anticp |
DVQPTLSPGDR | 0.63 | 1184.26 | − 1 | 3.71 | Non-toxin | AIP | Anticp |
DVTVLDNTDGK | 0.62 | 1176.23 | − 2 | 3.41 | Non-toxin | Non-AIP | Anticp |
EDLVSK | 0.62 | 689.75 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
EDLVSKDDVVIK | 0.61 | 1359.52 | − 2 | 3.82 | Non-toxin | AIP | Anticp |
EDLVSKDDVVIKS | 0.6 | 1446.6 | − 2 | 3.82 | Non-toxin | AIP | Anticp |
ELAVVSPIQFR | 0.59 | 1258.47 | 0 | 6.86 | Non-toxin | AIP | Anticp |
ELTPGAATTLEGK | 0.59 | 1287.42 | − 1 | 4.15 | Non-toxin | AIP | Anticp |
ENIDELKDTR | 0.58 | 1232.3 | − 2 | 3.93 | Non-toxin | AIP | Anticp |
ENLHLPLPLL | 0.58 | 1158.39 | − 0.9 | 5.1 | Non-toxin | AIP | Anticp |
ENLHLPLPLLQ | 0.58 | 1286.52 | − 0.9 | 5.1 | Non-toxin | AIP | Anticp |
EPIPYPILP | 0.58 | 1038.24 | − 1 | 1.1 | Non-toxin | AIP | Anticp |
EPVPDPVR | 0.57 | 908.01 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
EPVPDPVRG | 0.57 | 965.06 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
ETAAEVELR | 0.56 | 1017.09 | − 2 | 3.85 | Non-toxin | AIP | Anticp |
ETIIPK | 0.56 | 699.84 | 0 | 6.85 | Non-toxin | AIP | Anticp |
ETMDFLK | 0.55 | 883.02 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
FE | 0.54 | 294.3 | − 1 | pH 1 | Non-toxin | AIP | Anticp |
FLDDDLTDDK | 0.54 | 1196.22 | − 4 | 3.11 | Non-toxin | AIP | Anticp |
FLPPLQPAV | 0.53 | 981.19 | 0 | 3.41 | Non-toxin | AIP | Anticp |
FLPPLQPAVM | 0.52 | 1112.39 | 0 | 3.46 | Non-toxin | AIP | Anticp |
FPHASEVVKPQ | 0.52 | 1238.39 | 0.1 | 7.56 | Non-toxin | AIP | Anticp |
FQEPVPDPVR | 0.52 | 1183.31 | − 1 | 3.93 | Non-toxin | AIP | Anticp |
FRQENIDELK | 0.51 | 1291.41 | − 1 | 4.32 | Non-toxin | AIP | Anticp |
FRQENIDELKDTR | 0.51 | 1663.79 | − 1 | 4.44 | Non-toxin | AIP | Anticp |
GAHAGPTWNPISI | 0.51 | 1320.45 | 0.1 | 7.81 | Non-toxin | AIP | Anticp |
GLFQ | 0.51 | 463.53 | 0 | 3.7 | Non-toxin | AIP | Non-Anticp |
GLHPVPQP | 0.5 | 843.97 | 0.1 | 7.81 | Non-toxin | AIP | Non-Anticp |
GLHPVPQPLV | 0.5 | 1056.26 | 0.1 | 7.81 | Non-toxin | AIP | Non-Anticp |
P-5.2 | |||||||
LRPFL | 0.93 | 644.81 | 1 | 0.84 | Non-toxin | AIP | Anticp |
LRFPL | 0.91 | 644.81 | 1 | 0.84 | Non-toxin | AIP | Anticp |
LC | 0.84 | 234.32 | − 0.1 | 3.11 | Non-toxin | AIP | Anticp |
HSGF | 0.81 | 446.46 | 0.1 | 7.56 | Non-toxin | AIP | Anticp |
LWKL | 0.79 | 558.71 | 1 | 0.12 | Non-toxin | AIP | Anticp |
PLLL | 0.74 | 454.6 | 0 | 4.08 | Non-toxin | AIP | Anticp |
ESLPGVPPPSGQPLL | 0.74 | 1487.7 | − 1 | 0.92 | Non-toxin | Non-AIP | Anticp |
KPVMECGALLL | 0.7 | 1173.49 | − 0.1 | 6.12 | Non-toxin | AIP | Anticp |
CHLL | 0.68 | 484.62 | 0 | 7.09 | Non-toxin | AIP | Anticp |
CFNTLMLPPEPLL | 0.67 | 1487.83 | − 1.1 | 0.92 | Non-toxin | AIP | Anticp |
SHGM | 0.66 | 430.48 | 0.1 | 7.54 | Non-toxin | AIP | Anticp |
QVNLPLTGGML | 0.64 | 1142.37 | 0 | 3.34 | Non-toxin | AIP | Anticp |
HSYAEEPPLYPLL | 0.63 | 1528.7 | − 1.9 | 4.14 | Non-toxin | AIP | Anticp |
DLPLMT | 0.6 | 688.84 | − 1 | 0.75 | Non-toxin | Non-AIP | Anticp |
NNLPLTM | 0.58 | 801.95 | 0 | 3.29 | Non-toxin | AIP | Anticp |
PLMLPLHQPL | 0.57 | 1158.46 | 0.1 | 8.26 | Non-toxin | AIP | Anticp |
DLLPLTM | 0.57 | 801.99 | − 1 | 0.78 | Non-toxin | AIP | Anticp |
FLEL | 0.55 | 520.62 | − 1 | 0.92 | Non-toxin | AIP | Anticp |
NHCDEPVPMT | 0.54 | 1142.27 | − 2 | 3.92 | Non-toxin | AIP | Anticp |
