Figure 2 | Scientific Reports

Figure 2

From: Field size effects on DNA damage and proliferation in normal human cell populations irradiated with X-ray microbeams

Figure 2

Effects of X-irradiated field sizes on the DNA damage response. The cells were irradiated with 1 Gy of X-rays at a dose rate of 0.25 Gy/s. The number of 53BP1 foci as DSB per cell was measured at 1 h (A), 4 h (B), 24 (C) and 48 h (D) post-irradiation. The data were obtained from three or four independent experiments and the mean values for each experiment were plotted. Open circles indicate the number of 53BP1 foci per cell in X-irradiated cells. The change in the number of 53BP1 foci depending on the field size were plotted with the best estimates (solid line) using the generalized linear models. These figures were created with KaleidaGraph ver.4.5.2.

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