Figure 3
DSB repair curves for each X-irradiated field size. (A) The DSB repair curves were created by combining A-D in Fig. 2. The results were represented as mean ± standard error. Lower triangle, Triangle, Square, and Rhombus indicates the number 53BP1 foci per cell of X-irradiated cells in 0.02 mm2, 0.09 mm2, 0.81 mm2, and 1.89 mm2, respectively. The number of 53BP1 foci per cell in sham-irradiated controls is Closed circle. (B) The DSB repair curves focused on 24- to 48-h after X-irradiation. At 1.89 mm2 and 0.81 mm2, the number of 53BP1 foci were significantly higher than background level at 48 h after X-irradiation (p < 0.05, t-test). These figures were created with KaleidaGraph ver.4.5.2.
