Figure 3 | Scientific Reports

Figure 3

From: Plasma biomarkers for prediction of early tumor recurrence after resection of pancreatic ductal adenocarcinoma

Figure 3

Gene expression analysis of patient-derived PDAC organoid cultures. The mRNA levels in seven organoid cultures (late recurrence: L1, L2, L3/early recurrence: E1, E2, E3, E4) were determined by qPCR for the genes MAEA, NT5E, AZU1, ATP6AP2, MICA, IFNLR1, CTSO, CDCP1 and TNFRSF12A. A ductal organoid line from a chronic pancreatitis patient (ctrl) served as control. The expression level of each gene was normalized against β-actin. Data is presented as mean ± SEM (n = 3), except AZU1 for E4, L2, L3 (n = 1). For each gene of interest, graphs on the left depict results for individual organoid lines, and graphs on the right a merged analysis including statistics. Statistical evaluation was performed using Student’s t-test: *p < 0.05; **p < 0.01; ***p < 0.001.

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