Figure 3

Localization of secondary CPP in HepG2 cells. HepG2 cells without incubation with secondary CPP (A) and 12 h (B) and 24 h (C) after addition of 100 μg/mL secondary CPP. TEM imaging showed extracellular crystalline-like structures (arrowhead) around treated HepG2 cells (B, C), whereas no such structure was present in control cells (A).