Table 2 Plasma bilirubin with regard to medication and tobacco use in individuals with FEP.

From: Plasma bilirubin levels are reduced in first-episode psychosis patients and associates to working memory and duration of untreated psychosis

Medication/tobacco

Median [Interquartile range] (n)

Plasma bilirubin levels (µmol/l)

p valuea

FEP patients on drug or on tobacco

FEP patients off drug or off tobacco

Antipsychoticsb

10.0 [10.0–13.0] (16)

11.0 [8.0–12.0] (23)

0.70

Antidepressantsc

12.5 [10.0–16.5] (4)

10.0 [9.0–12.0] (35)

0.31

Antiepilepticsd

8.0 (1)

11.0 [9.0–13.0] (38)

0.25

Benzodiazepinese

12.0 [9.0–16.0] (11)

10.5 [9.0–12.0] (28)

0.46

Zopiclone

11.0 [10.0–13.0] (10)

10.0 [9.0–12.0] (29)

0.18

Phenothiazine derivatesf

10.0 [10.0–13.0] (11)

11.0 [9.0–12.5] (28)

0.73

Any treatmentsg

11.0 [9.0–13.0] (27)

10.5 [7.0–14.0] (12)

0.62

Tobacco

10.0 [9.5–11.5] (12)

11.0 [8.5–12.5] (24)

0.74

  1. Abbreviations: FEP, First-episode psychosis; (n), number. aMann-Whitney U-test, two-sided. bAll antipsychotics combined. cAll antidepressants combined. dAll antiepileptic’s combined. eAll benzodiazepines combined. fAll Phenothiazine derivatives combined. gEither N, AD, AE, BZD, Z, PD or a combination of these drugs.
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