Table 1 Reactivity classification of the CCP samples.

CCP #	VITROS CoV2T S/C ratio	VITROS CoV2T interpretation	RVPN NT50	RVPNT interpretation	COVAM RF probability	COVAM RF interpretation	Concordance
CCP #	VITROS CoV2T S/C ratio	VITROS CoV2T interpretation	RVPN NT50	RVPNT interpretation	COVAM RF probability	COVAM RF interpretation	CoV2T vs RVPNT	CoV2T vs COVAM rf	RVPNT vs COVAM rf
1	0.01	Non-Reactive	< 40	Non-reactive	0.796	Reactive	1	0	0
2	0.02	Non-Reactive	< 40	Non-reactive	0.21	Non-reactive	1	1	1
3	0.31	Non-Reactive	< 40	Non-reactive	0.38	Non-reactive	1	1	1
4	1.39	Reactive	279.5	Reactive	0.996	Reactive	1	1	1
5	1.45	Reactive	145.5	Reactive	0.402	Non-reactive	1	0	0
6	2.14	Reactive	302.4	Reactive	0.996	Reactive	1	1	1
7	2.77	Reactive	4171	Reactive	1	Reactive	1	1	1
8	4.24	Reactive	< 40	Non-reactive	0.86	Reactive	0	1	0
9	4.48	Reactive	< 40	Non-reactive	0.836	Reactive	0	1	0
10	5.21	Reactive	617	Reactive	1	Reactive	1	1	1
11	5.36	Reactive	132.2	Reactive	0.402	Non-reactive	1	0	0
12	5.62	Reactive	3583	Reactive	1	Reactive	1	1	1
13	6.22	Reactive	97.58	Reactive	0.868	Reactive	1	1	1
14	7.54	Reactive	< 40	Non-reactive	0.848	Reactive	0	1	0
15	9.37	Reactive	< 40	Non-reactive	0.372	Non-reactive	0	0	1
16	9.45	Reactive	< 40	Non-reactive	0.966	Reactive	0	1	0
17	9.8	Reactive	132.8	Reactive	0.984	Reactive	1	1	1
18	10.3	Reactive	< 40	Non-reactive	0.602	Reactive	0	1	0
19	11	Reactive	6910	Reactive	1	Reactive	1	1	1
20	12.4	Reactive	< 40	Non-reactive	0.95	Reactive	0	1	0
21–99	12.9–436	Reactive	> 131	Reactive	0.8—1	Reactive	79	79	79
						% concordance	93%	96%	91%

CCP samples were analyzed by the COVAM array as well as the VITROS CoV2T chemiluminescence and RVPNT assays. The results from the two computational methods as well as VITROS and RVPNT assays show high concordance, especially for the high titer samples. A higher concordance (96%) was observed between the VITROS assay and COVAM array.

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