Figure 5 | Scientific Reports

Figure 5

From: An acute phase protein α1-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action

Figure 5

Administration of hAGP rescues renal inflammation at day 14 after renal-IR in AGP KO mice. The mRNA expression of (A) IL-6, (B) TNF-α, (C) IL-1β and (D) F4/80 in the kidney at day 14 after renal IR were determined by real-time PCR. hAGP administration to AGP KO mice (2 mg/mouse/day, ip, from day 0 (before IR) to day 7) suppressed IR-induced renal inflammation. Data are expressed as the means ± SE (n = 4–8).

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