Figure 5

Protein–protein interaction network of the discriminant proteins found to correspond to the MALDI-TOF spectral peaks recognized as significant by the trained classifiers. (A) 3D homology structures of the 12 discriminant proteins. (B) The Protein–protein interaction network showing the 12 discriminant proteins (blue circles) and the 239 S. uberis proteins (red circles) to which they interact with (first shell interacting partners). Amongst these first shell interacting partners, two proteins—SUB1644 (ksgA) and SUB1631 (fusA)—are related to antimicrobial resistance.