Figure 2 | Scientific Reports

Figure 2

From: Molecular mechanisms detected in yak lung tissue via transcriptome-wide analysis provide insights into adaptation to high altitudes

Figure 2

The function of differentially expressed mRNAs was analyzed by KEGG and GO enrichment. GO enrichment of comparison between yak and cattle (A) and comparison among yaks living at three different altitudes (B). The results from the enrichment analysis are presented using an enrichment cycle diagram. Four circles were included from the outside to the inside. The first circle indicates the enrichment classification. The number of genes (scale) is shown outside of the circle. Different colors represent different categories. The second circle shows the number of background genes in the categories and their Q or P values. A longer bar indicates a higher number of genes, and a redder color indicates a smaller value. The third circle shows the total number of differentially expressed genes in the categories. The fourth circle presents the RichFactor value of each category (the number of differentially expressed genes in this category divided by the number of background genes). Each small grid of auxiliary background lines represents 0.1. Analysis of significantly enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of comparison between yak and cattle (C) and comparison among yaks living at three different altitudes (D). The significantly enriched KEGG pathways had P values < 0.05. Each line represents a gene, and the number of lines indicates the enriched genes. GO and KEGG analysis was visualized by the OmicShare tools, a free online platform for data analysis (http://www.omicshare.com/tools).

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