Table 2 Outcomes of linear regression analyses, adjusted for particle size, for the association between cell responses and the properties of the coal particles the cells were exposed to (pyrite content and bioavailable iron).
From: No association between pyrite content and lung cell responses to coal particles
Cell type | Outcome | Pyrite | Bioavailable Iron | ||
|---|---|---|---|---|---|
β [95% CI] | p | β [95% CI] | p | ||
Epithelial cells | Cytotoxicity | 0 [− 0.01, 0.01] | 0.61 | 0.06 [− 0.05, 0.18] | 0.24 |
IL-8 | − 1.31 [− 10.66, 8.03] | 0.75 | 121.03 [40.49, 201.62] | 0.01 | |
Macrophages | Cytotoxicity | 0 [0, 0] | 0.18 | − 0.02 [− 0.16, 0.17] | 0.67 |
IL-8 | − 4.64 [− 17.24, 7.97] | 0.41 | − 299.78 [− 747.81, 148.24] | 0.16 | |
Fibroblasts | Proliferation | 0 [− 0.02, 0.02] | 0.78 | − 0.04 [− 0.30, 0.22] | 0.74 |
Collagen | − 0.83 [− 1.96, 0.30] | 0.13 | 0.71 [− 18.68, 20.09] | 0.93 | |
