Table 3 Mean neurite formation defect scores for kinase inhibitors targeting the Aurora and Nuak kinases reveal possible defects in neurite initiation and/or elongation.

From: High-throughput kinase inhibitor screening reveals roles for Aurora and Nuak kinases in neurite initiation and dendritic branching

Kinase inhibitor targets

Average score

Possible defect

DMSO control

5.04

N/A

Aurora Kinase A

3.69

Neurite elongation

Aurora Kinase B

1.22

Neurite initiation

Aurora Kinase A/B

1.18

Neurite initiation

Aurora Kinase B/C

3.74

Neurite elongation

Aurora Kinase A/B/C

1.46

Neurite initiation

Nuak 1

1.09

Neurite initiation

Nuak 1/2

3.43

Neurite elongation

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