Figure 5
From: 3D cell sheet structure augments mesenchymal stem cell cytokine production
Cell sheet contraction increases actual cytokine production by hUC-MSCs. Human VEGF secretion was increased (a) 2.1-fold per hUC-MSC in 3D cell sheets compared to 2D monolayers cultured for 24 h. (b) The hUC-MSC proliferation rate during this time course was significantly higher in 2D monolayers compared to 3D cell sheets. Values are means ± SE (n = 3: *p < 0.05 and ***p < 0.001).
