Table 1 Demographic data of thalassemia patients.

From: An association between fibroblast growth factor 21 and cognitive impairment in iron-overload thalassemia

Patient characteristics

n = 131

Gender, n (%)

Male

43 (32.8)

Female

88 (67.2)

Age (year)

35 ± 11

Education, n (%)

Primary education

23 (17.5)

Junior high school

11 (8.4)

Senior high school

36 (27.5)

Bachelor’s degree

58 (44.3)

Master’s degree

3 (2.3)

Thalassemia typing, n(%)

Hemoglobin H

22 (16.8)

Beta thalassemia/hemoglobin E

82 (62.6)

Homozygous beta-thalassemia

27 (20.6)

Splenectomy, n(%)

Yes

64 (48.9)

No

67 (51.1)

Transfusion dependent, n(%)

Yes

79 (60.3)

No

52 (39.7)

Hemoglobin (g/dl)

7.2 ± 1.3

Hematocrit (%)

23.2 ± 4.9

Serum ferritin (ng/ml)

1324 (1497)

Maximum level of serum ferritin in the past 5 years (ng/ml)

1959 (2221)

Iron chelating agents, n(%)

Deferoxamine

8 (6.1)

Deferiprone

48 (36.6)

Deferasirox

11 (8.4)

Deferoxamine + deferiprone

21 (16.0)

Deferoxamine + deferasirox

12 (9.2)

No

31 (23.7)

  1. Data from age, hemoglobin, hematocrit, and MoCA score were represented by mean ± SD, while data from serum ferritin and Maximum level of serum ferritin in the past 5 years were represented as median and IQR.
  2. MoCA montreal cognitive assessment.