Table 1 Clinical characteristics of participants.

From: Detection of pro angiogenic and inflammatory biomarkers in patients with CKD

 

CKD

Post-transplant CKD

Healthy control

p value (ANOVA)

Stage 3 and 4

Stage 3 and 4

(n = 16)

(n = 16)

(n = 16)

A: Original cohort

Age (years)

58 ± 17

52 ± 14

36 ± 14

0.0017

Gender (female %)

31%

50%

75%

0.05

Race (Caucasian %)

81%

100%

88%

0.45

History of DM (%)

47%

7%

0%

0.001

BMI (kg/m2)

29.0 ± 5.3

25.9 ± 4.3

25.2 ± 5.8

0.1

SBP (mmHg)

131 ± 14

135 ± 14

115 ± 12

0.0006

DBP (mmHg)

80 ± 8

83 ± 10

71 ± 8

0.002

CKD-EPI eGFR (mL/min/1.73m2)

41 ± 9

49 ± 10

100 ± 17

< 0.0001

ACR (mg/g)

6 ± 17

1 ± 3

0.1 ± 0.1

0.02

ACEi/ARB (%)

73

30

0

< 0.0001

B: Validation Cohort* (n = 30)

Age (years)

64 ± 9

Gender (female %)

32%

Race (Caucasian %)

92%

History of DM (%)

39%

BMI (kg/m2)

29.8 ± 4.5

SBP (mmHg)

137 ± 15

DBP (mmHg)

76 ± 9

CKD-EPI eGFR (mL/min/1.73m2)

36 ± 11

ACR (mg/g)

7.5 ± 17

ACEi/ARB (%)

64

  1. Values are expressed as means ± standard deviation or % = percent of patients; DM = diabetes mellitus; BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; CKD-EPI eGFR = CKD-EPI estimated glomerular filtration rate; ACR = urinary albumin/creatinine ratio; ACEi: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor II blocker.
  2. *CKD only.