Table 4 Proteins identified to be significantly different for EVs of CKD versus EVs of healthy control.

From: Detection of pro angiogenic and inflammatory biomarkers in patients with CKD

Target

CKD patients relative to healthy

Biological pathways

CKD/healthy fold change

p value

CFD

2.3

< 0.0001

Immune regulation

REN

2.2

< 0.0001

Hemodynamic regulation

β2-microglobulin

2.0

0.0001

Inflammation

PRSS2

2.0

< 0.0001

Immune system, inflammation

Cystatin-C

2.0

< 0.0001

Protein degradation

TNFRSF1B

1.7

0.0001

Apoptosis

  1. The data are shown ratiometrically for relative fluorescence units (RFU) for CKD/healthy control. IGFBP: insulin-like growth factor binding protein, CFD: complement factor D, REN: renin, TNFRSF1B: tumor necrosis factor receptor superfamily member 1B.
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