Table 4 Predictors of LAA% rapid progression by univariate and multivariate logistic regression analysis.

From: Characteristics of chronic obstructive pulmonary disease patients with robust progression of emphysematous change

Parameters

Univariate analysis Odds Ratio (95% CI)

P-value

Age

1.74 (0.29–10.41)

0.54

Sex, female

2.40 (0.91–6.33)

0.08

BMI

0.47 (0.08–2.64)

0.39

FFMI

0.46 (0.07–3.04)

0.42

Pack-year

0.57 (0.08–4.40)

0.59

Current smoker

1.06 (0.36–3.08)

0.92

Osteoporosis or Osteopenia vs normal

2.20 (1.14–4.25)

0.02

%FEV1 < 70%

1.06 (0.57–1.97)

0.84

Low Attenuation Area > 10%

1.33 (0.72–2.48)

0.36

Low Attenuation Area > 20%

1.37 (0.70–2.68)

0.37

Blood eosinophil count < 300 cells/mm3

2.75 (1.02–7.45)

0.03

Bronchodilator (%)

1.29 (0.65–2.54)

0.46

ICS, N %

0.80 (0.38–1.65)

0.54

Parameters

Multivariate analysis Odds Ratio (95% CI)

P-value

Osteoporosis or Osteopenia vs normal

2.13 (1.09–4.14)

0.03

Blood eosinophil count < 300 cells/mm3

3.22 (1.07–9.66)

0.04

  1. BMI body mass index, CI confidence interval, FFMI fat-free mass index, %FEV1 forced expiratory volume in 1 s as a percentage of predicted forced expiratory volume in 1 s, LAA% the ratio of low attenuation area to total lung volume, ICS inhaled corticosteroids.
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