Figure 3 | Scientific Reports

Figure 3

From: The combination of fluoxetine and environmental enrichment reduces postpartum stress-related behaviors through the oxytocinergic system and HPA axis in mice

Figure 3

The effects of treatment with oxytocin receptor antagonist (OXT-A) following gestational stress, and fluoxetine treatment plus environmental enrichment (FLX + EE) on anxiety-like behavior in the open field test (A; inner zone time) and depression-like behavior in the social interaction (B; total interaction time), sucrose preference (C), and forced swim test (D; immobility time) during the postpartum period in dams. Values are presented as mean ± SEM (N = 10). Significant differences: *P < 0.05 and **P < 0.01, compared to non-stress group; + P < 0.05 and +  + P < 0.01, compared to stress group; &P < 0.05 and &&P < 0.01, compared to stress + FLX + EE + vehicle group.

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