Figure 5 | Scientific Reports

Figure 5

From: The combination of fluoxetine and environmental enrichment reduces postpartum stress-related behaviors through the oxytocinergic system and HPA axis in mice

Figure 5

Experiment 1 tested the effects of gestational stress, fluoxetine treatment and environmental enrichment on anxiety (open field test), depression-like behavior (social interaction and sucrose preference, forced swim test), HPA-axis function (serum ACTH and corticosterone), and oxytocin in the brain during the postpartum period in dams. Experiment 2 investigated the FLX + EE mediated alleviation of the negative effects of gestational stress through blocking oxytocin receptor on anxiety and depression-like behavior, and HPA-axis function during the postpartum period in dams.

Back to article page