Figure 4
From: Characterization of an anterior segment organ culture model for open globe injuries
Mechanical property changes after OG injury in ASOC injury platform. (A) Average IOP relative to baseline levels immediately after injury and 24, 48, and 72 h post injury for control, small, medium, and large injury sizes. (B) Summary of statistical difference for IOP data for each injury state vs. its time matched control. p values for the injury and time effect on IOP are also shown, as determined by 2-way ANOVA. (C) Ocular compliance and (D) calculated durations per unit IOP from 18 to 15 mmHg for control, small, medium, large OG injury sizes immediately post injury (D3 organ culture) and 3 days post injury (D6 organ culture). Durations are logarithmically plotted to better show large and small values on a single plot. Results are shown as mean and error bars denote standard deviation throughout. Asterisks denote (*) p < 0.05, (**) p < 0.01, (***) p < 0.001, and (****) p < 0.0001 as determined by two-way ANOVA, post-hoc Dunnett’s test.
