Figure 8 | Scientific Reports

Figure 8

From: Characterization of an anterior segment organ culture model for open globe injuries

Figure 8

Effect of Dermabond tissue sealant on maintaining IOP and Ocular compliance. (A) Average IOP relative to baseline levels immediately after injury and 24, 48, and 72 h post injury for untreated and Dermabond treated tissue. (B) Summary of p values for Dermabond vs. untreated time-matched controls, as well as the effect of therapeutic and time on IOP, as determined by two-way ANOVA, post-hoc Šídák method. Values are bolded when statistically significant (p < 0.05) (C) Each of 5 Dermabond treated replicate responses across the 72 h following injury and treatment to highlight the variability between the replicates. (D) Ocular compliance for untreated and Dermabond treated tissue immediately post injury (D3 organ culture) and 72 h post injury (D6 organ culture). Results are shown as mean and error bars denote standard deviation throughout.

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