Table 6 Overall survival, progression free survival and malignant progression free survival at 3, 5 and 10 years after surgery in patients with total resection, stratified according to molecular diagnosis (WHO 2016).

From: Multimodal integrated approaches in low grade glioma surgery

 

Among patients with EOR = 100%

% (95% CI)

DA IDHwt

DA IDHmt

OA IDHmt 1p19q cod

Number of patients

12

45

37

Overall survival %(95%CI)

3 years

91.67 (53.90–98.78)

97.56 (83.92–99.65)

100.00 (-)

5 years

91.67 (53.90–98.78)

91.76 (76.39–97.29)

100.00 (-)

10 years

91.67 (53.90–98.78)

87.59 (69.47–95.29)

86.54 (55.83–96.48)

Progression free survival %(95%CI)

3 years

91.67 (53.90–98.78)

88.15 (73.83–94.89)

93.94 (77.69–98.47)

5 years

82.50 (46.09–95.33)

62.40 (43.68–76.45)

77.18 (55.45–89.25)

10 years

68.75 (29.07–89.26)

51.51 (30.79–68.82)

26.23 (7.52–50.06)

Malignant progression free survival %(95%CI)

3 years

91.67 (53.90–98.78)

92.85 (79.43–97.64)

96.67 (78.61–99.52)

5 years

91.67 (53.90–98.78)

85.97 (68.99–94.03)

96.67 (78.61–99.52)

10 years

91.67 (53.90–98.78)

71.05 (42.29–87.30)

70.86 (41.90–87.25)

  1. Table showing overall survival, progression free survival and malignant progression free survival at 3, 5 and 10 years after surgery according to molecular diagnosis (WHO 2016), in patients with Extent of Resection = 100%.
  2. EOR extent of resection, DA IDHwt Diffuse Astrocytoma Isocitrate Dehydrogenase wild type, DA IDHmt Diffuse Astrocytoma Isocitrate Dehydrogenase mutated, OD IDHmt 1p19q cod Oligodendroglioma Isocitrate Dehydrogenase mutated, 1p 19q codeleted.