Figure 4

Odds ratios for medical history among top and bottom half groups of plasma EC-SOD concentration in SOD3 p.R231G non-carriers in the Very Old and Centenarians. Total number of SOD3 p.R231G non-carriers in Very Old and Centenarians was 453 and 549, respectively. The results in the “Crude” column indicate the results analyzed using the generalized linear model without adjustment factor and the results in the “Adjusted” column indicate the results analyzed using the generalized linear model adjusted with age, sex, and educational history. The black circles and lines in the figure indicate the odds ratio (OR) and range for 95% confidence interval (CI) in the “Adjusted” results, respectively. These results suggest that plasma EC-SOD concentration in the SOD3 p.R231G variant non-carriers is associated with a high odds ratio for CKD in both the Very Old and Centenarians, while higher plasma EC-SOD concentration is only associated with low odds ratio for DM only in the Very Old.