Figure 7
From: Selection of aptamers against triple negative breast cancer cells using high throughput sequencing

In vitro toxicity of Apt1 and Apt2. (A) Cell viability was evaluated by MTT assay. MDA-MB-231 cells were incubated with Apt1 and Apt2, respectively, for 24 and 48 h. The ssDNA library was used as a negative control. All data are expressed as the mean ± SD of three independent experiments. Two-way ANOVA indicates statistically significant differences within the group assessed by Sidak’s post-test and denoted as follows: *ρ ≤ 0.1 and ns ρ > 0.05. (B) Microscopy images of MDA-MB-231 cells treated with Apt1 or Apt2 for 0 h, 3 h, 6 h, 8 h, and 24 h. Non-treated cells were used as negative controls.