Table 2 Cytokine concentrations in cortex and thalamus of saline and buprenorphine treated animals at 1d following CFPI.

From: Buprenorphine alters microglia and astrocytes acutely following diffuse traumatic brain injury

 

Cortex

Thalamus

Saline

Buprenorphine

Saline

Buprenorphine

IL-1b pg/mg

14.40 (4.44)

14.40 (11.45)

0.36 (0.50) #

2.29 (2.29) #

IL-4 pg/mg

12.78 (6.23)

12.97 (2.51)

1.13 (1.15) #

3.63 (3.29) #

IL-10 pg/mg

17.12 (7.71)

18.69 (3.79)

4.36 (2.77) #

5.23 (3.83) #

IL-12 pg/mg

36.93 (23.04)

33.41 (28.87)

19.64 (43.93)

2.84 (6.35)

  1. n = 6 rats/group. Data presented as mean (SD) pg of cytokine per mg of total protein. Regional differences: #p < 0.05 compared to cortex.