Figure 6
From: Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels
Pressure overload increased PDGFRa-derived cells in the adventitia. (A) Schematic outlining the experimental strategy. (B) Hematoxylin eosin-stained ascending aorta at 28 days after TAC surgery. Asc Aorta: ascending aorta. Scale bar: 100 µm. (C) Fluorescence image showing the distribution of tdTomato+ cells at 28 days after TAC surgery. Asc Aorta: ascending aorta. Scale bar: 100 µm. (D–F) Immunostaining for Sca1 (D), αSMA (E), SM-MHC (F) on ascending aorta sections at 28 days after TAC surgery. L: lumen, I: intima, M: media, A: adventitia, Asc Aorta: ascending aorta. Scale bars: 20 µm. See also Figure S5.
