Table 2 The sex-specific estimates of hazard ratios (HR) for colorectal cancer risk in specific mutation carriers compared to non-mutation carriers.

From: Cumulative risks of colorectal cancer in Han Chinese patients with Lynch syndrome in Taiwan

Sex

MMR mutation carriers

MLH1 mutation carriers

MSH2 mutation carriers

HR (95% CI)*

HR (95% CI)*

HR (95% CI)*

Male

23.2 (9.2–58.2)

24.2 (9.8–60.1)

38.2 (12.2–119.9)

Female

13.2 (5.9–29.6)

15.0 (6.4–35.4)

27.9 (10.1–76.9)

  1. MMR; Mismatch repair genes.
  2. Including MLH1 and MSH2.
  3. *Estimation of HR was adjusted for ethnicity and physical activity.