Table 4 Multivariable logistic regression analyses of frailty parameters predicting the occurrence of adverse health events (N = 402).

From: Several frailty parameters highly prevalent in middle age (50–65) are independent predictors of adverse events

 

Composite outcomea

Non-accidental falls

Adjusted OR [95% CI]

p-value

Adjusted OR [95% CI]

p-value

Female sex

2.67 [1.17–6.11]

0.02

8.07 [1.74–37.5]

0.008

Living alone

2.39 [1.32–4.33]

0.004

2.39 [1.22–4.69]

0.01

Balance impairment (ankle dorsiflexion < 20°)

2.09 [1.16–3.78]

0.02

1.80 [0.91–3.57]

0.09

Executive function impairment (FAB score < 16)

2.61 [1.18–5.77]

0.02

2.48 [1.02–6.06]

0.046

Exhaustion

2.98 [1.65–5.39]

 < 0.001

2.32 [1.15–4.68]

0.02

  1. OR odds ratio, CI confidence interval, FAB frontal assessment battery.
  2. aThe composite outcome comprised the following adverse events: non-accidental falls (those not related to sports, DIY, or domestic accidents), fractures (hip, spine, and wrist), unplanned hospital admissions, and death. Some patients had multiple events.
  3. Multivariable models (after multiple imputation for missing data) were also adjusted for length of follow-up.