Figure 3

(a) CT-scan of abdomen in patient 102 before baseline (left panel), at baseline (middle panel) and first evaluation at week 8 (right panel). This patient fulfilled the criterion for hyperprogressive disease. (b) CT-scan of abdomen in patient 109 before baseline (left panel), at baseline (middle panel) and first evaluation at wee 8 (right panel). This patient fulfilled the criterion for hyperprogressive disease.