Table 1 Clinical characteristics of 93 ALL patients.

From: Recurrent somatic mutations and low germline predisposition mutations in Korean ALL patients

 

Childhood

Adult

Sex

Male

35

10

Female

30

18

Diagnosis

B-ALL, NOS

25

8

B-ALL with t(9;22)(q34.1;q11.2); BCR-ABL1

2

11

B-ALL with t(v;11q23.3); KMT2A rearranged

4

1

B-ALL with t(12;21)(p13.2;q22.1); ETV6-RUNX1

9

 

B-ALL with hyperdiploidy

16

1

B-ALL with t(1;19)(q23;p13.3); TCF3-PBX1

2

2

T-ALL

5

5

Early T-cell precursor acute leukemia

2

 

Cytogenetic risk group (B-ALL)

Good

26

2

Intermediate

26

9

High

6

12

 

65

28

  1. (1) good risk—ETV6-RUNX1 and high hyperdiploidy (51–65 chromosomes); (2) intermediate risk—TCF3-PBX1, IGH translocations, B-other (none of these established abnormalities); (3) high risk—BCR-ABL1, KMT2A translocations, near haploidy (30–39 chromosomes), low hypodiploidy (less than 30 chromosomes), iAMP21, TCF3-HLF.
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