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Figure 1

From: Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort

Figure 1

Breast cancer case–control and TNBC case-series risk analysis of previously identified BC risk alleles among our ICSBCS cohort. (A) The log odds ratio (x-axis) depicting SNV association with BC- or TNBC-risk among all samples is shown in non-adjusted models, and models adjusted for covariates (race and age) in our BC case–control analysis (left) and TNBC case-series analysis (right). (B) Within SIR BC case–control risk analysis for rs4849887. (C) Within SIR TNBC case-series analysis for rs2363956. For both (B) and (C), non-adjusted and age-adjusted models within SIR groups are shown for African Americans (AA), European Americans (EA), and Ghanaians (labelled as G). In our TNBC case-series analysis among SIR AA, we additionally adjusted for West African ancestry (WAa).

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