Figure 1
From: Modeling and live imaging of mechanical instabilities in the zebrafish aorta during hematopoiesis
Illustration of zebrafish embryonic dorsal aorta and cardinal vein at 50 hpf. HSPC production is accompanied by a collective cell migration toward the ventral part of the DA and an emergence of the periodic pattern of alternating thinner and thicker regions with a well-defined wave vector. Cells that undergo endothelial-to-hematopoietic transition leave the aorta and enter the cardinal vein becoming HSPCs (shown through a longitudinal section in the cardinal vein). Horizontal yellow arrows show blood flow direction.
