Figure 2

CaCO3 nanoparticle characterization. (A) Transmission electron microscope image of nanoCaCO3 dispersed in ethanol before drying the nanoparticles shows spherical particles with the size of 78.6ā±ā7.6Ā nm. Scale barā=ā200Ā nm (main panel); 100Ā nm (inset). (B) NanoCaCO3 were dispersed in ethanol for dynamic light scattering measurement, showing an average intensity-based size of 120.0Ā nmā±ā29.3Ā nm. Average number of particles-based size measurement is 101.8ā±ā24.7Ā nm (not shown). (CāF) TEM images of nanoCaCO3 after dispersion in distilled water (C), PBS (D), serum (E), and DMEM (F); scale barsā=ā100Ā nm for (C) and 500Ā nm for (DāF).