Table 1 Clinical and demographic characteristics of MMN patients.
From: Long-term treatment with subcutaneous immunoglobulin in multifocal motor neuropathy
Pt | Age at baseline (years) | Sex | Comorbidity | Age at disease onset | First diagnosis | Onset symptoms | Secondary symptoms | Sensory symptoms | Latency onset/secondary symptoms | Latency onset/FLT | Present phenotype |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 53 | F | – | 36 yrs | Carpal tunnel syndrome | Fasciculations UL and LL | Proximal right UL weakness and burning | Yes | 3 yrs | 11 yrs | Proximal and distal right and left UL weakness, distal left LL weakness |
2 | 74 (d) | M | Diabetes, cutaneous t cell lymphoma | 64 yrs | MMN | Distal right UL weakness and paresthesias | Distal left UL weakness and paresthesias | Yes | 1 yrs | 0 | Tetraparesis |
3 | 48 | F | – | 40 yrs | Cervical radiculopathy | Distal right UL weakness | Proximal right UL weakness ad cramps | – | 5 yrs | 5 yrs | Weakness Proximally at right UL and lower limbs and distally at upper limbs and left LL |
4 | 80 (d) | M | Autoimmune hypothyroidism | 58 yrs | MMN | Fasciculations, proximal left UL weakness, distal left LL weakness, dysesthesias at left hand and foot | Distal right UL weakness and paresthesias | Yes | 5 yrs | 2.5 yrs | Proximal weakness at left UL, distal weakness at right UL and lower limbs |
5 | 59 | M | – | 52 yrs | Right plexopathy/2nd motoneuron disease | Distal right UL weakness | – | – | – | 9.5 yrs | Distal right UL weakness |
6 | 61 | M | Diabetes | 45 yrs | MMN | Proximal right UL weakness and pain | Proximal left UL weakness and pain, motor disturbances at lower limbs | – | 1 month | 2 yrs | Proximal and distal weakness at the 4 limbs |
7 | 31 | M | – | 29 yrs | MMN | Distal left LL weakness | Distal left UL weakness | – | 1 yrs | 1 yrs | Distal weakness at left UL and lower limbs |
8 | 41 | M | – | 33 yrs | MMN | Proximal right LL weakness | Proximal right and left UL weakness, distal right UL weakness | Yes | 7 yrs | 2 yrs | Right hemiatrophy of the tongue. Proximal and distal upper and lower limbs weakness. Hypoesthesia in right ulnar nerve territory and from both knees to feet |
