Table 2 Distribution of TLS patients grouped by WBC count.

From: Clinical characteristics of tumor lysis syndrome in childhood acute lymphoblastic leukemia

 

WBC < 50 × 109/L (n = 36, %)

WBC ≥ 50 × 109/L (n = 43, %)

OR (95% CI)

Age

≥ 1

97.2

86.0

1.00

< 1

2.8

14.0

5.7 (0.7–49.6)

Sex

Female

33.3

25.6

1.00

Male

66.7

74.4

1.5 (0.5–3.9)

Extramedullary infiltrationa

No

91.7

83.7

1.00

Yes

8.3

16.3

2.1 (0.5–9.0)

Immunophenotype

B

77.8

32.6

1.00

T

22.2

67.4

7.3 (2.6–19.9)

Hyperkalemia

No

75.0

55.8

1.00

Yes

25.0

44.2

2.4 (0.9–6.2)

Hyperphosphatemia

No

44.4

23.3

1.00

Yes

55.6

76.7

2.6 (1.0–6.9)

Hyperuricemia

No

38.9

48.8

1.00

Yes

61.1

51.2

0.7 (0.3–1.6)

Hypocalcemia

No

72.2

32.6

1.00

Yes

27.8

67.4

5.4 (2.0–14.2)

  1. aThe meaning of extramedullary infiltration was CNS/Testicular leukemia, mediastinal mass as well as enlarged spleen/liver.
  2. Bold values denote significant difference between groups.