Table 3 Difference of biochemical values among patients with/without clinical symptom of TLS.

From: Clinical characteristics of tumor lysis syndrome in childhood acute lymphoblastic leukemia

 

Arrhythmias

P

Seizures

P

Elevated creatinine

P

Oliguria

P

Yes (6)

No (73)

Yes (3)

No (76)

Yes (33)

No (46)

Yes (8)

No (71)

K (mmol/L)

4.5 ± 1.6

5.3 ± 1.3

0.173

6.1 ± 2.2

5.2 ± 1.3

0.259

5.7 ± 1.4

4.8 ± 1.1

0.004

6.5 ± 1.2

5.1 ± 1.3

0.005

Ca (mmol/L)

2.1 ± 0.6

1.8 ± 0.6

0.181

1.5 ± 0.8

1.8 ± 0.6

0.316

1.5 ± 0.6

2.0 ± 0.4

< 0.001

1.4 ± 0.6

1.8 ± 0.5

0.036

Pa (mmol/L)

1.7 (1.4–2.2)

3.3 (2.1–4.2)

0.009

b

2.7 (1.9–4.2)

0.586

4.2 (3.2–5.2)

2.1 (1.6–2.7)

< 0.001

4.2 (2.2–4.3)

2.7 (1.9–4.2)

0.125

UAa (umol/L)

358.4 (104.2–682.9)

644.8 (352.3–914.4)

0.116

b

541.0 (344.2–874.0)

0.712

764.0 (495.0–1180.3)

414.0 (224.3–588.3)

< 0.001

785.9 (498.5–1192.0)

504.7 (326.5–821.1)

0.105

  1. K potassium, Ca calcium, P phosphorus, UA uric acid.
  2. aRepresented by median (25–75 centile) because of non-normal distribution.
  3. bNumber of data was too small to be represented by 25–75 centile.
  4. Bold values denote significant difference between groups.