Table 2 Heart rate variability (HRV) and Baroreflex Sensitivity (alpha-index) in all groups.

From: Cholinergic stimulation with pyridostigmine modulates a heart-spleen axis after acute myocardial infarction in spontaneous hypertensive rats

 

Sham (n = 5)

AMI (n = 6)

AMI + PY (n = 5)

HRV

RMSSD (ms)

6.2 ± 2.0

5.8 ± 2.2

9.3 ± 2.0 *#

PIVAR (ms2)

28.5 ± 13.0

15.8 ± 6.0

63 ± 28.1 *#

LF (nu)

2.6 ± 2.0

2.5 ± 1.0

7.8 ± 4.5 *#

HF (nu)

9.7 ± 3.6

6.0 ± 3.0

23.9 ± 8.7 *#

LF/HF

0.3 ± 0.1

0.5 ± 0.2 §

0.4 ± 0.2

ALPHA-INDEX (ms/mmHg)

0.5 ± 0.3

0.6 ± 0.2

1.1 ± 0.5 *#

  1. Values expressed as mean ± SEM. §AMI vs Sham; *AMI + PY vs Sham and #AMI + PY vs AMI. HRV: heart rate variability; RMSSD: square root of the mean of the sum of squares of the differences between successive pulse interval values; PIVAR: pulse interval variance; LF: Low Frequency nu: Normalized units; HF nu: high frequency in normalized units; LF/HF: autonomic balance. *P < 0.05; #P < 0.05; §P < 0.05. Statistical significance was determined by one-way ANOVA followed by a multiple comparisons test Tukey’s was performed using GraphPad Prism version 9.0.1. www.graphpad.com.
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