Figure 5 | Scientific Reports

Figure 5

From: Systematic integrated analyses of methylomic and transcriptomic impacts of early combined botanicals on estrogen receptor-negative mammary cancer

Figure 5

Differential DNA methylation analyses by RRBS across different treatment groups. (a) Bar plot representing different numbers of differentially hypomethylated and hypermethylated genes in BSp, GTPs and the combination (BSp + GTPs) treatment groups. The height in the bar plot represents the total number of differentially methylated genes in BSp (blue color), GTPs (pink color) and the combination (green color) treatment groups. (b) Pie charts representing the genomic distribution of hypo- and hypermethylated regions in the combination treatment (NDMRs = 4181) group. Grey color represents Intronic regions (35%), yellow color represents exonic regions (16%), blue color represents intergenic regions (32%) and orange color represents promoter regions (17%).

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