Table 5 Pathway enrichment analyses of overlapped genes between RRBS and RNA-seq data in the combination (BSp + GTPs) treatment group.
Gene symbol | Pathways related to gene symbol | p value for differential expression (combination vs control) |
|---|---|---|
Overlapping up-regulated DEGs and hypomethylated DMGs | ||
Pdx1 | Transcription, DNA-templated | 2.57E−08 |
Pdx1 | Negative regulation of transcription from RNA polymerase II promoter | 8.58E−07 |
Pdx1 | Positive regulation of DNA binding | 2.85E−06 |
Tmem132d | Negative regulation of phosphatase activity | 1.80E−04 |
Tmem132d | Regulation of gene expression | 3.34E−04 |
Pdx1 | Cell division | 4.38E−04 |
Overlapping down-regulated DEGs and hypermethylated DMGs | ||
Ndufa1 | Apoptosis | 5.06E−04 |
Ndufa1 | Oxidation-phosphorylation process | 5.74E−04 |
Rpl13 | Translation | 5.80E−04 |
Get4 | DNA methylation | 6.54E−04 |
