Figure 2 | Scientific Reports

Figure 2

From: Application of multiple omics and network projection analyses to drug repositioning for pathogenic mosquito-borne viruses

Figure 2

Signature genes and proteins by multiple omics analyses. Venn diagrams show the overlap of signature genes and proteins by multiple omics analyses for the five viruses: (a) DENV, (b) ZIKV, (c) WNV, (d) CHIV and (e) JEV. The number of signature genes obtained from transcriptomic data with significant differences is shown in the blue circle for infections. The number of signature proteins obtained from proteomics data is shown in the orange circle. The number of human proteins that interact with viral proteins in human–virus PPIs is shown in the green circle. (f) Venn diagram of common signature proteins, which represent the intersection between proteome and PPIs for the five viral infections. The total number of the unique proteins was 146 for the five viral infections.

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