Figure 2 | Scientific Reports

Figure 2

From: Phytochemicals from Ajwa dates pulp extract induce apoptosis in human triple-negative breast cancer by inhibiting AKT/mTOR pathway and modulating Bcl-2 family proteins

Figure 2

Microscopic observation and cytotoxic activity of different concentrations (10–25 mg/mL) of ADPE against MDA-MB-231 and PBMCs. (a) and (b) Photomicrograph of MDA-MB-231 cells treated with 10 to 25 mg/mL concentrations of ADPE at 24 and 48 h, respectively. Photomicrographs were taken with an inverted phase contrast microscope (Scale bar = 100 μm). (c) Percent cell viability of ADPE at various concentrations against MDA-MB-231 cells after 24 and 48 h incubation. (d) Dose response curve (Log concentration vs % cell viability) representing IC50 values of ADPE at 24 and 48 h incubation. (e) Photomicrograph of PBMCs treated at various concentrations of ADPE at 24 h (Scale bar = 100 μm). (f) Percent cell viability of ADPE at various concentrations against PBMCs after 24 h incubation. Values are expressed as mean ± SEM of three independent experiments. *p < 0.05 as compared to control.

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