Table 2 Surgery results for both groups.

From: Surgical outcomes of localization using indocyanine green fluorescence in breast conserving surgery: a prospective study

Characteristics

Total

ICG-F + SONO

SONO

p value

(n = 414)

(n = 114)

(n = 300)

n (%)

n (%)

n (%)

Localization rate

414 (100)

114 (100)

300 (100)

1

Frozen resection margin

Negative

327 (79.0)

102 (89.5)

225 (75.0)

< 0.01

Positive

87 (21.0)

12 (10.5)

75 (25.0)

 

Intra-op margin ( +) type

Precancerous lesion / LCIS

52 (59.8)

9 (75.0)

43 (57.3)

0.60

DCIS

23 (26.4)

2 (16.7)

21 (28.0)

 

Invasive

12 (13.8)

1 (8.3)

11 (14.7)

 

Intra-op further resection

No

334 (80.7)

104 (91.2)

230 (76.7)

< 0.01

Yes

80 (19.3)

10 (8.8)

70 (23.3)

 

Permanent resection margin

Negative

366 (88.4)

110 (96.5)

256 (85.3)

< 0.01

Positive

48 (11.6)

4 (3.5)

44 (14.7)

 

Permanent margin positive type

Precancerous lesion/LCIS

28 (58.3)

1 (25.0)

27 (61.4)

0.11

DCIS

12 (25.0)

1 (25.0)

11 (25.0)

 

Invasive

8 (16.7)

2 (50.0)

6 (13.6)

 

Re-operation

No

397 (95.9)

109 (95.6)

288 (96.0)

0.79

Yes

17 (4.1)

5 (4.4)

12 (4.0)

 

Re-operation pathology

No residual

8 (47.1)

4 (80.0)

4 (33.3)

0.13

Residual

9 (52.9)

1 (20.0)

8 (66.7)

 

Resection size (gross) (cm3)

Total

97.47 (12.22–722.50)

75.11 (12.22–325.12)

105.15 (17.61–722.50)

< 0.01

T stage

Tis

92.25 (12.22–722.5)

60.04 (12.22–189.00)

95.70 (18.00–722.50)

0.05

T1

84.5 (13.16–480.00)

69.00 (13.16–325.12)

97.95 (17.61–480.00)

< 0.01

T2

140.25 (22.68–432.00)

117.00 (54.00–252.00)

152.00 (22.68–432.00)

< 0.01

Resection mass size (gross) (cm3)

Missing cases

51

14

37

 

Total

2.16 (0.01–84.00)

1.20 (0.01–28.80)

2.60 (0.04–84.00)

< 0.01

T stage

Tis

1.47 (0.02–84.00)

0.50 (0.02–7.50)

1.65 (0.25–84.00)

< 0.01

T1

1.49 (0.01–60.78)

1.08 (0.01–28.80)

1.67 (0.04–60.78)

0.10

T2

7.91 (0.36–47.43)

6.72 (3.60–22.04)

8.10 (0.36–47.43)

0.12

Centralization

Missing cases

34

6

28

 
 

3.35 (0.30–27.70)

2.40 (0.30–10.40)

3.70 (0.30–27.70)

< 0.01

  1. ICG-F indocyanine green fluorescence, SONO sonography, LCIS lobular carcinoma in situ, DCIS ductal carcinoma in situ.