Table 1 Patient characteristics.
From: Histidine-rich glycoprotein as a prognostic biomarker for sepsis
Variable | Total | Sepsis | Severe sepsis | Septic shock |
|---|---|---|---|---|
N | 99 | 10 | 43 | 46 |
Age, years | 72.0 (64.0–78.0) | 75.0 (68.3–80.5) | 72.0 (64.0–80.0) | 71.0 (60.8–76.3) |
Male sex, n | 69 (69.7%) | 8 (80.0%) | 28 (65.1%) | 33 (71.7%) |
28-day death, days | 16 (16.2%) | 0 | 8 (18.6%) | 8 (17.4%) |
ICU stay, days | 10.0 (5.0–16.0) | 7.5 (3.8–15.5) | 11.0 (5.0–18.0) | 9.5 (5.0–16.0) |
APACHE II score | 25.0 (21.0–31.0) | 20.0 (13.5–21.8) | 24.0 (22.0–30.0) | 28.0 (21.5–34.5) |
SOFA score | 11.0 (8.0–13.0) | 4.5 (2.0–6.0) | 9.0 (7.0–12.0) | 13.0 (11.0–16.0) |
Source of infection, n (death) | 99 (16) | |||
Lung | 20 (4) | 3 | 7 (2) | 10 (2) |
Gastrointestinal | 19 (2) | 3 | 10 (1) | 6 (1) |
Hepatic | 1 | 0 | 0 | 1 |
Gallbladder | 8 | 0 | 3 | 5 |
Urinary | 14 (1) | 1 | 6 (1) | 7 |
Bone/soft tissue | 13 (2) | 2 | 5 (1) | 6 (1) |
Others | 24 (7) | 1 | 12 (3) | 11 (4) |
Ventilation, n | 53 (53.5%) | 5 (50.0%) | 23 (53.5%) | 25 (54.3%) |
Inotropes (Day 1) | 54 (54.5%) | 1 (10.0%) | 7 (16.3%) | 46 (100%) |
Blood purification | ||||
Chronic dialysis | 4 (4.0%) | 0 | 1 (2.3%) | 3 (6.5%) |
Renal replacement therapy | 29 (29.3%) | 0 | 15 (34.9%) | 14 (30.4%) |
Polymyxin B hemoperfusion | 7 (7.1%) | 0 | 3 (7.0%) | 4 (8.7%) |
Liver failure | 2 (2.0%) | 0 | 2 (4.7%) | 0 |
AIDS | 0 | 0 | 0 | 0 |
Hematologic malignancies | 6 (6.1%) | 1 (10.0%) | 1 (2.3%) | 4 (8.7%) |