Figure 6

Cellular density in healthy (A) and osteoarthritic (B) cartilage as a function of cellular organisation. P-values are listed in (C) with significant p-values denoted in bold. Significance was determined on an FDR-adjusted alpha (for absolute cell count values, see Table 1; for exact FDR-adjusted alphas, see supplementary Table 1). Abbreviations: SZH—superficial zone healthy cartilage; SSH—single strings healthy cartilage; SZ—superfical zone; SS—single strings; DS—double strings; SC—small clusters; LC—large clusters. Significant differences are listed in the table below. For zonal labelling according to the predominant regional pattern, see also supplementary Figure 5. This figure was created using SPSS Statistics 23 (https://www.ibm.com/ch-de/products/spss-statistics), Microsoft Office Word (https://www.microsoft.com/de-ch/microsoft-365/word) and Adobe Illustrator CS6 (https://www.adobe.com/ch_de/products/illustrator.html).