Table 1 Patient characteristics.

From: Successful elimination of bilirubin in critically ill patients with acute liver dysfunction using a cytokine adsorber and albumin dialysis: a pilot study

 

All patients: n (%) or median [range: min, max]

CytoSorb: n (%) or median [Range: min, max]

ADVOS: n (%) or median [Range: min, max]

Differences in both groups (p-value)

No. of patients

39 (100)

33 (100)

6 (100)

 

Age, years

55 [18, 80]

55 [18, 76]

46 [19, 80]

0.84

Gender, male/female

27 (69.2) / 12 (30.8)

23 (69.7)/10 (30.3)

4 (66.7) / 2 (33.3)

0.92

BMI, kg/m2

27.7 [16.2, 55.1]

27.8 [16.2, 55.1]

26.0 [18.8, 35.2]

0.56

ECMO therapy

11 (28.2)

10 (30.3)

1 (16.7)

0.61

7-days mortality

12 (30.8)

10 (30.3)

2 (33.3)

0.92

In-hospital mortality

32 (82.1)

28 (84.8)

4 (66.7)

0.51

SOFA score d0

20 [12, 23]

20 [12, 23]

21 [18, 23]

0.48

SAPS II d0

80 [47, 111]

80 [47, 109]

72 [50,111]

0.53

MELD score d0

35.0 [25.4, 52.9]

33.6 [25.4, 52.9]

38.5 [30.5, 44.8]

0.10

MELD score d1

34.4 [25.8, 52.3]

33.8 [25.8, 52.3]

38.5 [30.1, 45.8]

0.23

Total bilirubin (mg/dl) d-1

16.8 [4.2, 40.2]

14.2 [4.2, 40.2]

18.5 [11.7, 26.9]

0.35

Total bilirubin (mg/dl) d0

17.3 [10.2, 41.1]

16.9 [10.2, 41.1]

17.7 [10.7, 28.0]

0.89

Total bilirubin (mg/dl) d1

13.3 [5.2, 25.6]

13.2 [5.2, 25.6]

15.9 [6.8, 21.9]

0.81

  1. SOFA, sequential organ failure assessment; SAPS, Simplified Acute Physiology Score; ADVOS, advanced organ support; BMI, body mass index; ECMO, extracorporeal membrane oxygenation.