Figure 4
From: Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect

BTZ and CFZ induced proteasome inhibition in U266.B1 cells and sensory neurons. Proteasome inhibition of U266.B1 cells (A) and neurons (B) after treatment for 48 h with 2.8 nM BTZ or 3.2 nM CFZ. Graphs are represented as mean percentage ± SD compared to an untreated CTRL (arbitrarily set to 0%). **p < 0.01 versus CTRL