Table 1 Tubulin polymerization and depolymerization rate and lag.
From: Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect
| Â | Polymerization rate RFU% / min | Polymerization lag min | Depolymerization rate RFU% / min | Depolymerization lag min |
|---|---|---|---|---|
DMSO buffer | ||||
CTRL | 19.57 ± 0.29 | 0 | 9.05 ± 0.65 | 2.11 ± 0.25 |
BTZ | 23.62 ± 0.69 ** | 0 | 3.50 ± 0.12 ** | 9.45 ± 0.76 ** |
CFZ | 19.52 ± 0.88 | 0 | 10.07 ± 0.85 | 2.29 ± 0.87 |
