Table 1 The most frequently selected features that entered the model and their correlation with the estimated fitness.
Name | Number of appearance (out of 20) | Spearman correlation | P value |
|---|---|---|---|
Topological distance in the mRNA in position 865 ('mRNA_topo_dist_865') | 10 | 0.6824 | 8.534e−70 |
Bend angle difference in the DNA in position 822 ('DNA_topo_dist_BendAngle_pos_822') | 6 | 0.0435 | 0.3321 |
Mutation in position 785 ('mut_pos_785') | 6 | − 0.1435 | 0.0013 |
Folding energy difference in the DNA in position 779 ('DNA_FE_diff_779') | 5 | 0.1675 | 0.0002 |
Mutation in position 831 ('mut_pos_831') | 5 | 0.1240 | 0.0055 |
Mutation in position 849 ('mut_pos_849') | 5 | 0.0325 | 0.4685 |
Folding energy difference in the DNA in position 737 ('DNA_FE_diff_737') | 4 | − 0.1593 | 0.0003 |
Topological distance in the mRNA in position 839 ('mRNA_topo_dist_839') | 4 | 0.5965 | 1.64e−49 |
Mutation in position 813 ('mut_pos_813') | 4 | − 0.3942 | 4.89e−20 |