Table 1 Gene-environment interaction between genetic risk for psychiatric disease and gestational age at birth on cognition at four.

From: Greater genetic risk for adult psychiatric diseases increases vulnerability to adverse outcome after preterm birth

Psychiatric GPS

GPSpsych × GA

β3

SE

p3

ADHD

− 0.015

0.016

0.302

ASD

− 0.003

0.015

0.846

Bipolar Disorder

0.038

0.014

6.61 × 10–3

Major Depressive Disorder

0.001

0.014

0.958

Schizophrenia

0.038

0.013

6.85 × 10–3

  1. Results exploring the effect of the interaction term GPSpsych × GA on cognitive outcome in 4934 unrelated individuals. β3 is the estimate of the effect size of the interaction term GPSpsych × GA, SE is the standard error of the effect size and p3 is the corresponding p-value. Bonferroni correction was used to adjust for multiple testing and p-values < 0.01 (0.05/5) were considered statistically significant. Significant results are indicated in bold. Beta regression coefficients and associated p-values for all terms in the regression model are detailed in Supplementary Table S3 in the Supplementary Information.
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