Table 5 Multivariate analysis of factors associated with overall survival in osteosarcoma with inclusion of IMPDH2/HPRT ratio.

From: IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma

Factor

Overall survival

HR (95% CI)

P value

Age at diagnosis (years)

 ≤ 15

1.00

–

 > 15

1.36 (0.83–2.23)

0.216

Site

Extremities

1.00

–

Axial

0.92 (0.43–1.97)

0.841

Stage

IIB

1.00

–

III

2.38 (1.45–3.91)

0.001

Treatment completion

Completed

1.00

–

Not completed

3.03 (1.85–4.97)

< 0.001

IMPDH2/HPRT ratio

Low

1.00

–

High

1.67 (1.02–2.72)

0.039

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